Red seedless grapes are small to medium in size and are round to slightly oblong in shape, growing in medium to large clusters. The hue of a Red seedless grape can vary widely depending on the variety and local growing conditions, but it usually ranges from a light red to a deep burgundy. The thin skin may also contain a dusty film, also known as a bloom, and this layer forms a natural waterproof barrier which prevents the delicate skin from cracking. The translucent flesh is juicy and is considered seedless, though a few small undetectable and undeveloped seeds may be present. Red seedless grapes are firm, crisp, and sweet with a mild, neutral flavor.

Red seedless grapes contain significant amounts of vitamins A, C, and K, and contain flavonoids, such as resveratrol, which provide high antioxidant qualities that can help boost overall health.